Tinidazole, Thioconazole

Vaginal suppositories (suppositories) Gainomax are indicated for the treatment of:

• candida vulvovaginitis caused by pathogens of the family Candida albicans;
• bacterial vaginosis caused by pathogens of the family Gardnerella vaginalis and anaerobic bacteria;
• Trichomonas vaginitis caused by Trichomonas vaginalis;
• mixed infection vaginitis.

Structure

Active ingredients thioconazole and tinidazole;

1 vaginal suppository contains:

• thioconazole - 100 mg;
• tinidazole - 150 mg.

Excipients: vitepsol.

Contraindications

• Hypersensitivity to active ingredients or their derivatives.
• Drinking alcohol during treatment or within 3 days after treatment.
• Taking disulfiram during treatment or within 2 weeks after treatment.
• Porphyria.
• Epilepsy.
• Severe impairment of liver function.
• The first trimester of pregnancy.
• The period of breastfeeding.
• Organic diseases of the nervous system.
• Hematopoiesis disorders, including a history of.

Mode of application

For intravaginal use only. Gaynomax should be entered deep into the vagina in a prone position.

Introduce 1 candle for 7 days at bedtime. Alternative scheme: apply 1 suppository twice a day for 3 days.

Do not swallow or inject into other places.

Application features

Pregnant women

Contraindicated.

Children

Not applicable.

Drivers

Unknown

Overdose

Systemic side effects can be observed with the use of a large amount of the drug, but with intravaginal use, systemic side effects are not expected.

In case of an overdose, symptomatic and supportive therapy should be started. Side / unwanted effects in case of overdose are not known.

Side effects

• From the nervous system: weakness, increased fatigue, poor health, headache, dizziness.
• From the digestive system: metallic / bitter taste in the mouth, nausea, anorexia, loss of appetite, flatulence, dyspepsia, abdominal cramps, discomfort in the epigastric region, vomiting, constipation.
• From the kidneys and urinary system: dark color of urine.

Interaction

• Acenocumarol, anisindione, dicumarol, phenindione, fenprocoumone warfarin: increased risk of bleeding.
• Cholestyramine: decreased effectiveness of tinidazole.
• Cimetidine: increased concentration of tinidazole in blood plasma.
• Cyclosporin: increased levels of cyclosporin.
• Disulfiram: side effects from the central nervous system (e.g. psychotic reactions).
• Fluorouracil: an increase in the concentration of fluorouracil in the blood and signs of possible intoxication (granulocytopenia, anemia, thrombocytopenia, stomatitis, vomiting).
• Phosphenytoin: an increase in the toxicity of fosphenytoin and / or a decrease in the concentration of tinidazole in the blood.
• Ketoconazole: increased concentration of tinidazole in the blood.

Storage conditions

Store at a temperature below 25 ° C out of the reach of children.

Shelf life is 24 months.