Stifimol

Pharmacological properties

the main component of the drug is Garcinia cambogia extract (garcinia cambogia). This plant has been used for centuries in dietary and medicinal purposes in Southeast Asia. The main component of this extract is hydroxycitric acid, which inhibits lipogenesis, reduces the formation of cholesterol and fatty acids, increases glycogen production in the liver, reduces appetite, and increases the bodys heat production by activating thermogenesis.

Chromium picolinate regulates the absorption of glucose by the cells of the body and helps maintain a normal physiological level of glucose in the blood. Regulates carbohydrate, lipid, in particular cholesterol metabolism in the body. A thermosynergic mixture based on L-carnitine and L-tyrosine is used. A unique feature of L-carnitine is that it increases the permeability of cell membranes to fatty acids. L-Carnitine increases lipid utilization for energy supply and slows down the rate of synthesis of fat molecules in subcutaneous fat depots. When taking L-carnitine, a permanent loss of adipose tissue begins, the efficiency of fat oxidation in the body increases significantly, the production of free radicals decreases, and the ATP content increases.

L-tyrosine is a precursor to the neurotransmitters norepinephrine and dopamine. The biosynthesis of catecholamines begins with tyrosine. Administration of L-tyrosine improves catecholamine metabolism. One of the main target tissues of catecholamines in the body is fat. Adrenaline and norepinephrine stimulate lipolysis through β₁-adrenergic receptors that activate through the cAMP system (by phosphorylation) the hormone-sensitive lipase of triacylglycerols. Adrenaline also causes lipolysis of triacylglycerols in muscle cells through the cAMP system. Tyrosine suppresses appetite, promotes the production of melatonin, improves the function of the thyroid gland and adrenal glands. Thyroid hormone biosynthesis begins with tyrosine iodination. These hormones stimulate the metabolic processes in the body. Tyrosine takes part in the regulation of the emotional state: it helps to eliminate the feeling of anxiety and overcome depression.

Brown algae extract, due to the presence of iodine in its composition, improves the functioning of the thyroid gland, activates metabolic processes, and promotes lipid breakdown in adipose tissue.

Indications

The medicine is used:

• with excess body weight;
• tendency to obesity;
• during a diet to reduce appetite.

Application

In adults, take 1 capsule 2-3 times a day before meals, with a glass of water. the course of treatment is 4-6 weeks. repeated courses can be prescribed after a 2-3-month break.

Contraindications

Hypersensitivity to the components of the drug, including iodine.

Side effects

In recommended doses, the drug is well tolerated and rarely causes side effects, which are usually associated with individual intolerance to one of the components of the drug.

With individual hypersensitivity to the components of the drug, reactions are possible:

from the immune system: hypersensitivity reactions, including allergic and anaphylactic reactions, Quinckes edema, skin rashes, itching, urticaria.

From the endocrine system: hyperthyroidism and hypothyroidism induced by iodine.

From the cardiovascular system: increased blood pressure, tachycardia.

From the digestive tract: diarrhea.

special instructions

Caution should be exercised in patients with pathology of the thyroid gland, diseases of the cardiovascular system and disorders of the gastrointestinal tract. for diseases of the thyroid gland, the iodine content in the drug stifimol, which is 37 μg in 1 capsule, is taken into account.

The drug contains lactose, therefore it should not be used in patients with hereditary galactose intolerance, glucose-galactose malabsorption or lactase deficiency.

Use during pregnancy and lactation. Due to the lack of clinical data, the drug should not be taken during pregnancy and lactation.

Children. The drug is not used in children due to lack of data on its effectiveness and safety in this category of patients.

The ability to influence the reaction rate when driving or working with other mechanisms. No data available.

Interactions

When prescribing stifimol, it is advisable to take multivitamins with it. they must be used no earlier than 2 hours after taking stifimol. the simultaneous use of other iodine preparations and drugs that are taken for thyroid diseases should be avoided.

Overdose

Symptoms: with an overdose, adverse reactions from the thyroid gland (hyperthyroidism or hypothyroidism), the cardiovascular system (increased hell, tachycardia), gastrointestinal tract (diarrhea) are possible. if signs of an overdose appear, discontinue use of the drug.

Treatment: symptomatic.

Storage conditions

In the original packaging at a temperature not exceeding 25 ° C.