Solcovagin

Pharmacological properties

Solcovagin is a combined preparation for the local treatment of benign lesions of the cervix. due to its composition, Solcovagin acts differently on different types of cervical epithelium. after applying the drug to erosion and the transformation zone, Solcovagin causes an immediate intravital fixation of the ectopic cylindrical epithelium and subepithelial stroma.

The stratified squamous epithelium is sufficiently resistant to the action of the drug and practically does not undergo changes. The fixation process takes only a few minutes and is accompanied by a pale yellowish or gray staining of the tissue. Necrotic tissue is a protective layer, under which again the formation of a stratified squamous epithelium occurs. After a few days, the necrotic epithelium is desquamated.

Pharmacokinetics The acids and zinc nitrate that make up Solcovagin cause rapid devitalization and fixation of pathologically altered tissues. This process is probably not accompanied by significant absorption; given the minimum therapeutic dose, a systemic effect of the drug is unlikely.

Indications

Cervical ectopia; transformation zone; ovula nabothi (after opening); cervical canal polyps; postoperative granuloma (for example, after a hysterectomy).

Application

The drug is intended for topical use only and can be applied exclusively by a gynecologist. during the procedure, it is necessary to treat only the affected area, avoiding the penetration of the solution onto the skin of the external genital organs and vaginal epithelium.

Clean the cervix from the discharge with a cotton swab. Treatment of the cervix with 3% acetic acid rum makes it possible to more clearly define the boundaries of the lesion.

Impregnate Solcovagin with a cotton swab wound on a wooden stick. Treat the affected area.

After 1-2 minutes, repeat the treatment with a new cotton swab dipped in the Solcovagin solution.

Solcovagin treatment is carried out on an outpatient basis and does not include any restrictions on the use of water procedures and in sexual activity.

When treating erosion large in size and sufficiently deep, after the first course, it is recommended to monitor and repeat the treatment after 4-6 days.

The patient must again come for a follow-up examination 4 weeks after treatment. If the results of the examination are unsatisfactory, it is necessary to conduct a second course of treatment (2 applications) and then appoint a new follow-up visit after 4 weeks.

Order of use and destruction of packaging.

Open the bottle cap.

Soak a cotton swab.

After use, put a cotton swab into the bottle and break the wooden stick.

Close the bottle with rubber stopper to prevent Solcovagin residues from falling onto surrounding objects, then throw into the garbage container.

Contraindications

Hypersensitivity to the components of the drug. Solcovagin solution is contraindicated in patients with malignancy and cell dysplasia.

Side effects

When using Solcovagin, burning sensations, pain and itching are possible. excessive application can cause damage to deeper layers of tissue.

special instructions

Contact with the skin of the external genitalia and vaginal epithelium should be avoided. Solcovagin should not be applied to tissues in a state of inflammation. if pain is felt, treatment may be discontinued.

Attention! Improper use of Solcovagin (usually excessive application) can cause burns to the mucous membrane and damage to tissues under the epithelium.

Warning. The use of the drug does not lead to scarring or deformation of the cervical canal. Solcovagin is a preparation containing concentrated acids, therefore it is necessary to avoid contact of solution with clothes, skin and especially the mucous membrane of the eyes.In case of contact with the Solcovagin solution on the skin of the external genitalia or vaginal epithelium, immediately rinse the area with water. In case of contact with eyes, rinse immediately with water or better with a neutralizing solution, for example 1% sodium bicarbonate solution.

During pregnancy and breastfeeding. The use of the drug is contraindicated during pregnancy and lactation. Children. The drug is not used in children, since efficacy and safety for this category of patients have not been established.

The ability to influence the reaction rate when driving vehicles and working with mechanisms. No studies have been conducted.

Interactions

Unknown.

Overdose

An overdose of the drug is not possible, since one bottle contains the amount of solcovagin solution for only one procedure. but applying too much can cause a burning sensation, pain, and itching.

Storage conditions

At a temperature not exceeding 25 ° C. formation of a crystalline precipitate is possible, which is a consequence of temperature fluctuations (for example, a decrease in ambient temperature during transportation). short-term heating (1-2 minutes) to 40 ° C leads to the dissolution of the precipitate.