Sandy Helichrysum Concentrate

General characteristics:

basic physical and chemical properties: tablets of yellow or yellow with a brownish tint, interspersed, with a weak specific smell, flat-cylindrical shape, with a bevel;
composition: 1 tablet contains flaming in terms of the total amount of flavonoids 70% and dry matter - 50 mg;
excipients: lactose monohydrate, potato starch, corn starch, magnesium carbonate, calcium stearate.

Release form.
Tablets.

Pharmacotherapeutic group.
Means used in diseases of the liver and biliary tract. PBX code A05A X10.

Pharmacological properties.
Pharmacodynamics Flavone-containing polyphenolic drug from inflorescences of sandy cumin (Helichrysum; Helichrysum arenarium L.). It contains flavonoid glycosides (salipurposide, isosalipurposide, kempferol, apigenin), bitterness, tannins, sterols, essential oils and other biologically active substances (organic acids, carotenoids, polysaccharides, etc.).
It increases the secretion of bile, the osmotic gradient between bile and blood, which enhances the osmotic filtration into the bile capillaries of water and electrolytes, increases the flow of bile through the bile ducts, the content of cholates in the bile, reduces the possibility of precipitation of bile cholesterol (preventing the formation of gallstones). It has a relaxing effect on the smooth muscles of the sphincters of the gallbladder and biliary tract, changes the viscosity and chemical composition of bile. By stimulating the secretion of gastric juice and slowing down the evacuation function of the stomach and intestines, it contributes to better digestion of food. Contributing to the release of cholesterol with bile, has a hypocholesterolemic effect; possesses antibacterial activity against gram-positive bacteria, increases the activity of metronidazole and aminoquinol in the treatment of giardiasis.
Pharmacokinetics Not investigated.

Indications for use.
Chronic cholecystitis, biliary dyskinesia.

Dosage and administration.
Assign to adults and children over 5 years old inside, 30 minutes before meals, with a little water.
Adults are prescribed 50 mg (1 tablet) 3 times a day; if necessary, the dose can be increased to 100 mg (2 tablets) 2-3 times a day.
Children 5-10 years old are prescribed 50 mg (1 tablet) once a day, 10-14 years - 50 mg (1 tablet) 2 times a day.
The duration of treatment is 10–40 days (depending on the form and course of the disease). If necessary, the course of treatment can be repeated after a break of at least 5 days.

Side effect.
Rarely allergic reactions; increase in blood pressure (in patients with arterial hypertension).

Contraindications
Hypersensitivity to the drug, obstructive jaundice, exacerbation of peptic ulcer, acute inflammatory diseases of the liver and biliary tract. Childrens age up to 5 years.

Overdose.
Cases of overdose are not known.

Features of the application.
It is prescribed with caution to patients with increased acid-forming function of the stomach. Features of the drug during pregnancy and lactation have not been investigated, therefore, it is prescribed taking into account the risk / benefit ratio.
For children under 5 years of age, Flamin is prescribed in the form of granules for the preparation of an oral suspension.

Interaction with other drugs.
Flamin-Health can be used in combination with other drugs prescribed for diseases of the liver and biliary tract. Increases the activity of metronidazole and aminoquinol in the treatment of giardiasis.

Terms and conditions of storage.
Store in a dry, dark place at a temperature of 8 ° C to 25 ° C. Keep out of the reach of children.
Shelf life is 5 years.

Vacation terms.
Over the counter.

Packaging.
Tablets No. 30 in a plastic container and in a pack, No. 10 in a blister strip packaging No. 10x3 in a pack.