Fenilin® [Fenindion]
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Pharmacological properties
Phenindione (2-phenylindanedione-1,3) belongs to the group of indirect anticoagulants. causes hypoprothrombinemia due to a violation of the formation of prothrombin in the liver. a decrease in the concentration of coagulation factor occurs after 8-10 hours and reaches a maximum 24-30 hours after taking the drug.
Indications
Prevention and treatment of thrombosis, thrombophlebitis, thromboembolic complications in myocardial infarction. in surgical practice - to prevent thrombosis in the postoperative period.
Application
Inside - on the first day 0.12-0.2 g (in 3-4 doses), on the second day - in a daily dose of 0.09-0.15 g, then - 0.03-0.06 g / day depending on the level of prothrombin in the blood. for prophylactic purposes appoint 0.03 g 1-2 times a day.
Contraindications
Hemorrhagic diathesis, pregnancy, liver and kidney disease.
Side effects
Headache, nausea, diarrhea, fever, allergic skin reactions.
1337 Items
2020-07-30
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