Candid B® [Beclomethasone, Clotrimazole]

Pharmacological properties

Candid B is a combined antifungal drug for external use with an anti-inflammatory component. the pharmacological effect of the drug is due to the properties of clotrimazole and beclomethasone dipropionate, which are part of it. Clotrimazole is a broad-spectrum antifungal agent that belongs to the group of imidazole derivatives. Clotrimazole is susceptible to dermatophytes, yeast fungi (genus candida, torulopsis glabarata, rhodotorula), mold fungi, as well as pathogens of colorful lichen and erythrasma. in addition, clotrimazole is effective against gram-positive (staphylococci, streptococci) and gram-negative bacteria (bacteroides, gardnerella vaginalis), as well as against trichomonas vaginalis, malassezia furfur, corinebacterium minussimum. the effect of clotrimazole is associated with the ability to disrupt the synthesis of ergosterol, which is part of the cell membrane of fungi. as a result, the structure and properties of the membranes change, cell lysis is observed.

Beclomethasone dipropionate - a synthetic GCS - has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects.

Indications

Fungal infections of the skin, especially if they are accompanied by acute eczematous manifestations: dermatomycosis of various parts of the body, epidermophytosis of the feet, dermatosis complicated by a secondary infection.

Application

Apply externally 2-3 times a day. before use, it is necessary to wash and dry the affected area of ​​the skin, and then apply candida cream b. Candid B cream with occlusive dressings is not recommended. the duration of treatment of dermatoses is usually 3-4 weeks, erythrasma and pityriasis versicolor - about 3 weeks. there is no experience with the use of the drug in children.

Contraindications

Like other corticosteroids for topical use, candida b is not prescribed for cutaneous tuberculosis, chickenpox, herpes simplex, measles, post-vaccination reactions, syphilitic skin rashes. not used in individuals with hypersensitivity to any of the components of the drug.

Side effects

Candid B cream is generally well tolerated. rarely, with increased sensitivity to the components of the drug, local allergic reactions can occur - skin hyperemia, a burning sensation and tingling at the site of application of the drug. if side effects occur, the drug must be discontinued.

special instructions

The drug is intended for use only in dermatological practice.

After the disappearance of eczema, treatment can be continued with the use of monocomponent preparations of clotrimazole for external use. Although there is no data on the negative effects of local GCS during pregnancy, the safety of their use has not been established. Therefore, in high doses or or for a long time during pregnancy and lactation, the drug should not be prescribed.

Interactions

Not described.

Overdose

Acute overdose with topical application of candida cream is unlikely and poses no threat to life. local application of corticosteroids in large areas of the skin or under an occlusive dressing can lead to systemic absorption. when using occlusive dressings, a rash, folliculitis, or pyoderma can sometimes develop.

Storage conditions

In a dry, dark place at temperatures up to 25 ° C.