Avanafil

Avanalav tablets are used to treat erectile dysfunction in adult men. Sexual stimulation is needed to ensure the effectiveness of Avanalav®.

Structure

Active ingredient: Avanafil.

1 tablet contains - 100 mg of avanafil.

Excipients: mannitol (E 421), fumaric acid, hydroxypropyl cellulose, low-substituted hydroxypropyl cellulose, calcium carbonate, magnesium stearate, yellow iron oxide (E 172).

Contraindications

Hypersensitivity to the active substance or to any of the excipients of the drug.

The use of avanafil is contraindicated in these categories of patients:

• patients who have suffered a myocardial infarction, stroke, or life-threatening arrhythmia in the last 6 months;
• patients with arterial hypotension (blood pressure <90/50 mm Hg) or with hypertension (blood pressure> 170/100 mm Hg) at rest;
• patients with unstable angina pectoris, angina pectoris with sexual activity or congestive heart failure functional class 2 or higher (according to the classification of the New York Association of Cardiology).

Mode of application

The recommended dose is 100 mg, which is taken if necessary approximately 15-30 minutes before sexual activity. Given individual effectiveness and tolerance, the dose can be increased to a maximum of 200 mg or reduced to 50 mg. The maximum recommended frequency of use is 1 time per day. Sexual stimulation is needed to get a response to treatment.

Application features

Children

Do not prescribe to children (under the age of 18 years).

Overdose

In cases of overdose, if necessary, use standard supportive measures. It is not expected that hemodialysis accelerates the clearance of avanafil, since avanafil is largely associated with plasma proteins and is not excreted in the urine.

Avanafil was administered to healthy volunteers in single doses up to 800 mg, and in patients in multiple doses up to 300 mg per day. Adverse reactions were similar to those observed with low doses, but their frequency and severity increased.

Side effects

Increased levels of liver enzymes, abnormalities on the electrocardiogram, increased heart rate, increased blood pressure, presence of blood in the urine, heart murmur, increased prostate-specific antigen, increased body weight, increased levels of bilirubin in the blood, increased creatinine levels blood fever.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life is 2 years.