Artiflex

Artiflex is a combined three-component drug for the treatment of diseases of the musculoskeletal system. It contains glucosamine hydrochloride, ibuprofen and allantoin.

Active components

Due to the combined composition, the drug has chondroprotective, analgesic, anti-inflammatory, antiexudative, membrane-protective and antioxidant effects.

Glucosamine hydrochloride is a low molecular weight mucopolysaccharide that stimulates the regeneration of the joint bag and cartilage of the joint, and also inhibits the destruction of cartilage. Improves the synthesis of intraarticular fluid, which acts as a lubricant, improving joint gliding. Glucosamine hydrochloride increases the resistance of chondrocytes to the action of anti-inflammatory cytokinins and activates metabolic processes in the joint matrix, thereby contributing to the formation of a stable joint. Increases the elasticity and compression resistance of the cartilage, which are necessary to counter physical stress. Glucosamine hydrochloride has a moderate anti-inflammatory effect, therefore, enhances the effect of ibuprofen.

Ibuprofen has an analgesic and anti-inflammatory effect.

The analgesic effect of ibuprofen is associated with a decrease in the intensity of inflammation, a decrease in the production and weakening of specific pain mediators (analgesic bradykinin). It weakens the pain syndrome, including arthralgia at rest and during movement, reduces morning stiffness and swelling of the joint, and contributes to an increase in range of motion.

Allantoin is a herbal drug for comfrey.

It has anti-inflammatory properties, reduces pain, stimulates bone regeneration.

Methylpyrrolidinone is a transdermal substance that promotes the penetration of the active substances of the cream through the skin into the tissues of the joint.

Indications for use

Treatment of diseases of the musculoskeletal system, accompanied by signs of inflammation, swelling and pain, degenerative-dystrophic changes in the cartilage of the joints and spine, decreased joint mobility (osteoarthritis, arthropathy, intervertebral osteochondrosis).

Contraindications

• Hypersensitivity to the drug
• dermatosis, wet eczema;
• asthma and if NSAIDs can cause an asthma attack.

Dosage and administration

Apply the cream 2-3 times / day to the skin in the focus of inflammation and rub for 2-3 minutes. The course of treatment is 2 weeks.

special instructions

Do not apply cream to open wounds, avoid contact with mucous membranes.

Use with caution in concomitant kidney disease.

Do not exceed the recommended dose and duration of treatment. With prolonged use, the development of side effects of ibuprofen is possible.

The drug contains cetostearyl alcohol, which can lead to local skin reactions (eg contact dermatitis); methylparaben (E 218) and propyl paraben (E 216), which can cause allergic reactions (possibly delayed).

Structure

active substances: glucosamine, ibuprofen, allantoin;

1 g of the drug contains glucosamine hydrochloride 30 mg, ibuprofen 30 mg, allantoin 10 mg

excipients: glycerol monostearate, mineral oil, isopropyl myristate, cetostearyl alcohol, polyethylene glycol stearate, polysorbate 80, ethanol 96%, methyl paraben (E 218), propyl paraben (E 216), menthol, methylpyrrolidinone, purified sodium metabisulfite (22).

Storage conditions

Store in the original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life is 2 years.